乙氧甲叉丙二酸二乙酯制备方法的改进

Preparation of Ethoxymethytenemalonic Diethyl Ester

摘要: 乙氧甲叉丙二酸二乙酯是由丙二酸二乙酯和原甲酸三乙酯在乙酸酐和氯化锌催化下缩合而成的,收率97.3%(以丙二酸二乙酯计算)。原甲酸三乙酯的投料量是过量的,没反应的原甲酸三乙酯回收后套用在下一釜反应中。

Abstract: Ethoxymethylenemalonic diethyl ester is prepared by condensation of malonic diethyl ester and orthoformic triethyl ester in the presence of ZnCl_2 and acetic anhydride. The yield is 97.3% Which Calculates in terms of malomic diethyl ester. Orthoformic tri