硫酸锌缓释片研究

Researches on the Tablets of Sustained Release of Zinc Sulfate

摘要: 用高分子亲水性胶体作为主要骨架材料制备了硫酸锌骨架型缓释片SR-1 SR-2,用普通片C-T作对照,测定了SR-l、SR-2及C-T片的体外溶出累计百分率。用溶出速度参数T50作比较,SR-1,SR-2的缓释作用分别为普通片的4.7倍和2.8倍。锌含量测定采用锌试剂(zincon)紫外分光光度方法。

Abstract: Two kinds of zinc sulfate(ZS) sustained release tablets (SR-1, SR-2) were prepared by usingpolymolecular hydrophilic colloid as the major matrix materials. Dissolution studies of zinc ionfrom SR-1, SR-2 and conventional tablet (C-T) were carried out by ro