Abstract: OBJECTIVE To establish processing technology in production place of Corydalis Rhizoma. METHODS Compared different boiled processing time test, water steam test, sliced Sun-dried test, sulfur fumigation test or other processing test with the method of traditional processing. The best processing method was determined based on the content of effective constituents and extract content. RESULTS The effective constituent content of steam system processing samples and boiled samples presented the trend of decrease with the increasing of time, and both of them were higher than the traditional process. The content of water-extract in steam system processing was higher than that in boiled processing, but there was no remarkable difference between the boiling and the traditional processing. CONCLUSION Corydalis Rhizoma can be processed by steaming or boiling, but steaming is better. And the steaming or boiling time should not last for long time, otherwise it will result in the loss of active ingredients, and non-white inner core is used as the gold standard in steaming or boiling processing.