Abstract: OBJECTIVE To investigate the characteristics and regularity of adverse drug reaction(ADR) induced by cetuximab. METHODS Medication information of patients treated by cetuximab from January 2007 to June 2010 were retrospectively investigated by inpatient pharmacy dispensing system, then ADRs induced by cetuximab as well as relative ADR incidence rate, emergence time, clinical manifestation in 83 patients were analyzed. RESULTS The ADR incidence rate of cetuximab was 61.4%. The average of ADR emergence time was 19 days, the average accumulated dose when ADR occurred was 970 mg·m-2, the most common ADR was acneiform eruptions whose incidence rate was 59.0%. CONCLUSION Effective intervention treatment should be given before and after cetuximab therapy, so as to make the ADR incidence rate minimum and offer potent guarantee for clinical treatment.