大孔树脂对赤芍总苷吸附的初步研究

Research on Adsorption of Total Paeony Glycoside with Macroporous Resins

摘要: 目的研究D101、X-5、HPD-722、HP-20、AB-8、DM-130、HPD-600、NKA-9大孔树脂对赤芍总苷的吸附性能。方法以芍药苷和芍药内酯苷为考察指标，通过静态吸附及解析实验，动态吸附和解析实验，对大孔树脂纯化赤芍总苷的工艺进行筛选。结果 AB-8大孔树脂对芍药苷和芍药内酯苷的比吸附量分别为42.23，53.70 mg·mL^-1，比解析量分别为32.19，33.75 mg·mL^-1。结论 AB-8大孔树脂的对赤芍总苷的分离纯化效果较好，具有良好的应用前景。

Abstract: OBJECTIVE To investigate the adsorption of total paeony glycoside by D101, X-5, HPD-722, HP-20, AB-8, DM-130, HPD-600, NKA-9. METHODS Through static adsorption and desorption as well as dynamic adsorption and desorption, the purification of total paeony glycoside by AB-8 macroporous resin was selected with paeoniflorin and albiflorin as investigation targets. RESULTS The adsorption quantity of AB-8 resin for paeoniflorin and albiflorin was 42.23, 53.70 mg·mL^-1, and desorption quantity was 32.19, 33.75 mg·mL^-1. CONCLUSION The isolation and purification capability of AB-8 macroporous resin is the best in the eight kinds of macroporous resins and have a favourable application perspective.