Abstract: OBJECTIVE To understand comprehensively the related restrictions of toxic medical materials in the new version of "Chinese Pharmacopoeia", which will facilitate to control its toxicity effectively and ensure the safety of clinical application. METHODS To review and summarize the contents of using taboo on toxic medical materials in the 2010 version of "Chinese Pharmacopoeia". RESULTS The contents of using taboo on toxic medical materials in the 2010 version of "Chinese Pharmacopoeia" include that medication using taboos, special populations using taboos, disease taboos, patients constitution taboos and dietary taboos, which are important links on preventing the security risks of toxic medical materials. CONCLUSION The related restrictions of toxic medical materials in the new version of "Chinese Pharmacopoeia" is a kind of effective control measures from the standard levels, and is also an effective mean ensuring the safety of clinical medication, so we should obey them strictly in clinical use.