Abstract: In recent years, therapeutic drug monitoring(TDM) and precision medication have emerged as a key research focus in hospital pharmacy. As the diagnosis and treatment systems of medical institutions become increasingly refined, there is a growing demand for more professional and personalized pharmaceutical services. In order to advance the innovative development of TDM and precision medication, further enhance the quality of clinical pharmaceutical care, and foster the high-quality development of hospital pharmacy, this issue features a special column titled “Therapeutic Drug Monitoring and Precision Medication”. This special column focuses on three research dimensions including “expert consensus and research frontiers”, “method development and clinical application”, and “model construction and risk monitoring”. It widely solicits high-quality academic achievements, aiming to gather cutting-edge technologies, innovative methods, and practical experiences in the field, thereby providing references and insights for academic research and clinical practice in this domain.