Abstract: In medical practice, externally dispensed medications pose multiple potential legal risks in key links such as prescription circulation, drug quality, medication safety, and medical insurance compliance. To effectively address these risks, medical institutions need to make efforts in multiple aspects including system construction, technological upgrading, regulatory coordination, and personnel training: formulate a comprehensive External Medication Dispensing Management System and a standardized Informed Consent Form for External Medication Dispensing; accelerate access to the National Medical Insurance Electronic Prescription Center to promote the electronization, standardization, and full-process traceability of externally dispensed prescriptions; establish an “External Medication Dispensing Supervision Team” with coordination among multiple departments such as medical services, pharmacy, medical insurance, discipline inspection and information, and conduct regular reviews of externally dispensed prescriptions, risk screening, and analysis of typical cases; meanwhile, organize medical staff to participate in regular training on laws and regulations related to externally dispensed medications, so as to comprehensively improve their risk prevention and control capabilities.