OBJECTIVE  To evaluate clinical effectiveness of Longjin Tonglin capsules, aiming to explore their clinical advantages and promote rational drug use in clinical practice.

METHODS Evidence-based medicine, epidemiology and medical statistics were used to evaluate the efficacy, safety, economy, inheritance and innovation, suitability and accessibility of this product in treating prostatitis.

RESULTS  All the adverse reactions detected in the preclinical study and National Adverse Reaction Monitoring Center, were general and mainly concentrated in gastrointestinal system, the safety was rated as grade A. Efficacy evaluation showed that Longjin Tonglin capsules had curative effect in treating chronic prostatitis, which had been recommended by 3 guidelines and 4 experts. Literature research had showed that Longjin Tonglin capsules, in combination with western medicine were more effectively in treating prostatitis. Compared with the control group, the combination therapy significantly reduced the white blood cell count, pain scores, urinary symptom scores, and improved the quality of life impact scores. The effectiveness was rated as grade A. Economic evaluation showed that Longjin Tonglin capsules combined with conventional western medicine treatment of chronic prostatitis compared with conventional western medicine alone had cost-effective advantage. The economic performance was rated as grade A. The inheritance and innovation evaluation showed that Longjin Tonglin capsules originated from the folk prescription of Yi nationality in Yunnan Province, which had the effects of dispelling damp-heat, removing blood stasis and clearing shower. Longjin Tonglin capsules granted a patent, and had inheritance and innovation, innovation was rated as grade A. Suitability evaluation showed that the drug was capsule, patient compliance was good, its package insert met the current regulations, and the suitability was rated as grade A. The accessibility evaluation showed that Longjin Tonglin capsules had sustainable raw material resources, were sold in more than 30 provinces, autonomous regions, municipalities, and special administrative regions, and belonged to Class B drugs of medical insurance.The accessibility was rated as grade A.

CONCLUSION Longjin Tonglin capsules are derived from an ethnic folk prescription and have proven safe and effective clinically, which provides reference for drug selection and management.