OBJECTIVE  Exploring how the pharmaceutical manufacturing industry can exert the advantage of human capital to facilitate the digital transformation of enterprises in the digital context.

METHODS  Selected 58 pharmaceutical manufacturing companies listed on the Shenzhen and Shanghai stock exchanges as the research case, and used the fuzzy set qualitative comparative analysis(fsQCA) method to explore the configuration path of high digital transformation effectiveness from five aspects: knowledge-based human capital, technical human capital, employee ability, human capital allocation scale, and executive team stability.

RESULTS  There were 6 paths to produce high digital transformation effect, and enterprises should choose the corresponding configuration path for transformation and upgrading; Employee competence was a necessary condition for high digital transformation effectiveness; There were two second-order equivalent configurations, the non-high human capital allocation scale and high management team stability in H3 could replace each other, and the high knowledge human capital and high technology human capital in H4 could replace each other.

CONCLUSION  Pharmaceutical manufacturing enterprises should attach importance to the synergy of the five aspects of human capital, focus on enhancing employees' capabilities, and effectively promote the digital transformation of the enterprise.