OBJECTIVE  To explore an identification flow chart of drug induced pseudo-hypertriglyceridemia(Pseudo-HTG), which would help clinical pharmacists assist physicians to identify and manage drug induced Pseudo-HTG. Besides, several pharmaceutical care ways were proposed to provide reference for for the work entry and monitoring of clinical pharmacists.

METHODS  A patient with Pseudo-HTG induced by glycerol excipients was introduced, and drug induced Pseudo-HTG literatures were reviewed. The clinical and biochemical characteristics of drug induced Pseudo-HTG were summarized to determine the correlation between HTG and drugs.

RESULTS The history of alcohol consumption and renal dysfunction were high-risk factors for Pseudo-HTG. Triglyceride value of drug induced Pseudo-HTG could usually recover within 3–5 d after exogenous intake discontinue. However, the recovery time of patients with renal dysfunction who did not receive continuous renal replacement therapy might be extended to several months.

CONCLUSION  The clinical identification of drug induced Pseudo-HTG requires collaboration between physicians and pharmacists. The excessive intake of exogenous drugs with glycerol and the use of drugs may lead to drug induced Pseudo-HTG. Clinical pharmacists can enter the pharmaceutical monitoring work of Pseudo HTG patients from the aspects of establishing excipient databases, tracking cutting-edge pharmaceutical research, patient education, and medication monitoring.