OBJECTIVE To analyze the literatures related to Spatholobi Caulis published at home and abroad from 1992 to 2022, and to provide reference for exploring its research hotspot and frontier development trend.

METHODS Comprehensive retrieval of China network(CNKI) and Web of Science(WoS) related literature, using CiteSpace 6.2.R3 software, bibliometric tools and Excel of Chinese and English publications, journals, research authors, research institutions and keywords, post countries content knowledge map, and according to the method of extracting information of blood rattan research status and frontier development trend was analyzed.

RESULTS A total of 520 Chinese and 38 English articles were included. The annual publication volume of Spatholobi Caulis research in both databases demonstrated a linear growth trend as visualized through line charts, indicating increasing scholarly interest in recent years. The most prolific journals published Chinese and English literatures were Shaanxi Journal of Traditional Chinese Medicine and Journal of Pharmaceutical and Biomedical Analysis, respectively. The authors who had published the most Chinese and English literatures were Liu Junmin and Cai Zhichen, respectively. The research institutions that had published the most Chinese and English literatures were the School of Chinese Materia Medica, Guangzhou University of Chinese Medicine and China Academy of Chinese Medical Sciences, respectively. Keyword analysis revealed primary research foci: quality standards of medicinal materials, compatibility of herbal formulas, extraction of bioactive compounds, clinical application patterns, modern pharmacological effects, metabolomics, pharmacokinetics, signaling pathways, apoptosis, and antitumor mechanisms. Contributing countries included China, South Korea, Vietnam, Hungary, Iraq, Pakistan, Singapore, and the United States.

CONCLUSION Research on Spatholobi Caulis has expanded into multidisciplinary and multi-level investigations, yet inter-institutional and cross-team collaborations remain limited. Future hotspots and frontiers are anticipated to concentrate on pharmacological mechanisms, antioxidant stress, signaling pathways, anti-apoptotic mechanisms, and antitumor applications.