Abstract: Taurine is an abundant free amino acid in the body. It has many physiological functions and plays an important role in regulating lipid metabolism. Taurine can promote the biotransformation of cholesterol to bile acids and produce taurine-conjugated bile acids with bile acids. It can reduce liver fat accumulation and significantly improve obesity. This paper summarizes the pharmacological effects, clinical application and analysis methods of taurine and its derivatives, especially the mechanism of its effect on lipid metabolism, and reviews the related research on the effect of traditional Chinese medicine and its compound on lipid metabolism disorder by regulating taurine and hypotaurine metabolic pathways. Taurine has a very good application prospect in regulating lipid metabolism disorders. Taurine and hypotaurine metabolic pathways are important pathways for the regulation of lipid metabolism disorders. This review provides a theoretical basis for the in-depth study and clinical application of taurine and provides a reference for the development of related drugs and health products.