武汉33家医院执行质子泵抑制剂集采政策的效果评估

林智娟; 刘立; 贺文娟; 张志亮; 郭朝晖; 刘萍; 雷荃; 徐颖

doi:10.13748/j.cnki.issn1007-7693.20230019

武汉33家医院执行质子泵抑制剂集采政策的效果评估

Evaluation of the Effect for National Centralized Drug Procurement Policy of PPIs in 33 Hospitals in Wuhan

摘要

摘要:
目的分析执行国家药品集中带量采购政策后，质子泵抑制剂(proton pump inhibitors，PPIs)在湖北省武汉市33家医院的使用状况及发展趋势，为推动后续集采药品合理使用及完善相关政策提供参考。
方法对武汉市33家医院2019年及2022年PPIs采购金额、用药频度、限定日费用、使用率等进行统计、分析。
结果执行集采政策后，PPIs采购总金额下降53.6%，用药频度降低15.4%，限定日费用降低45.2%，注射剂型PPIs使用率下降12.6%。集采后口服剂型使用率增长最快的是奥美拉唑(5.7%)，其次是雷贝拉唑(5.0%)；而注射剂型的使用率差异较大，集采品种明显下降，非集采品种则显著上升。武汉市PPIs整体集采使用率为64.9%，不同等级医院间相差不大。
结论集采政策达到了降低患者用药成本、提高药品可及性的目的，在剂型选择上更加优化，整体符合政策预期；但集采后武汉市PPIs量价齐降，而且在品种选择上凸显了一定的倾向性。今后尚需优化措施，引导临床优先选用集采药品，保障和完善集采政策的实施。

Abstract:
OBJECTIVE To analyze the use status and development trend of proton pump inhibitors(PPIs) in 33 hospitals in Wuhan, Hubei Province after the implementation of the national centralized drug procurement(NCDP) policy, and to provide reference for promoting the subsequent rational use of NCDP drugs and improving related policies.
METHODS To make statistics and analysis of purchasing amount of PPIs, defined daily dose system(DDDs), defined daily dose consumption(DDDc) and utilization rate of 33 hospitals in Wuhan in 2019 and 2022.
RESULTS After the implementation of the NCDP policy, the total purchasing amount of PPIs decreased by 53.6%, DDDs decreased by 15.4%, DDDc decreased by 45.2%, and the utilization rate of PPIs injectable dosage forms decreased by 12.6%. After NCDP, the highest growth rate of oral dosage forms was omeprazole(5.7%), followed by rabeprazole(5.0%), while injectable dosage forms showed a significant difference in utilization rate, with a significant decline in NCDP varieties and a significant increase in non-NCDP varieties. The overall NCDP utilization rate of PPIs in Wuhan was 64.9%, with little difference among hospitals of different grades.
CONCLUSION The NCDP policy achieves the purpose of reducing the drug cost of patients and improving the accessibility of drugs, and is more optimized in the selection of dosage forms, which is in line with the policy expectations overall; but the quantity and price of PPIs in Wuhan decreased after NCDP, and highlighted a certain tendency in the selection of varieties. In the future, we still need to optimize measures to guide clinical priority in the selection of NCDP drugs, to ensure and improve the implementation of NCDP policy.

HTML全文

参考文献(29)

施引文献

资源附件(0)