Abstract: Prodigiosin(PG) represents a family of occurring red pigments produced by microbial secondary metabolism. PG has been demonstrated valuable biological activities as antitumor effect, antibacterial, antimalaria, antialgae, anti-insect and immunosuppressive activities. However, PG is insoluble and/or hardly soluble in water, poor stability, easier degradation and limit its ability to treat in functional status. Therefore, it is urgent to clarify the structure, characteristics and transport system of PG. This paper analyzed the structure of PG and summarized the existing transportation systems in order to understand PG and improve function, so as to provide theoretical support for further expanding the application of PG in medicine and food field.