Abstract: OBJECTIVE To conduct the comprehensive clinical evaluation of oral dihydropyridine calcium channel blockers and to provide reference for rational use of antihypertensive drugs in medical institutions. METHODS Led by the Second Affiliated Hospital of Nanchang University, supported by Jiangxi Research Hospital Association and Pharmacoepidemiology Committee of Jiangxi Pharmaceutical Society, and 25 third grade class A hospitals in Jiangxi Province jointly participated, using literature review and Delphi method, through kick-off meeting, two rounds of revision discussion and one round of electronic feedback after draft was completed. Expert Consensus was finally formulated. RESULTS As of February 2022, there were 2 oral dihydropyridine calcium channel blockers that had been included in the centralized drug volume-based procurement of the state. The expert consensus adopted the percentage system for quantitative evaluation. The comprehensive clinical evaluation on 10 oral dihydropyridine calcium channel blockers involved in centralized drug volume-based procurement in Jiangxi Province was implemented from six dimensions including effectiveness, safety, economy, suitability, accessibility and innovation, and different recommendation levels were formed according to the scores. CONCLUSION The Expert consensus on the comprehensive clinical evaluation of oral dihydropyridine calcium channel blockers under the centralized drug volume-based procurement policy in Jiangxi Province is established, which provides reference for the adjustment of the agreed procurement volume of centralized procurement at the national and provincial levels, and also provides theoretical basis for the formulation of the medical structure drug allocation and procurement catalogue, scientific and refined drug management.