Abstract: OBJECTIVE To develop an APP for assisting doctors, pharmacists and patients in managing daily antiepileptic drug treatment. METHODS Antiepileptic medication management APP was developed by Android Studio, Flutter, JAVA, Kotlin software, and the previously established population pharmacokinetic models of valproic acid, carbamazepine, oxcarbazepine and lamotrigine were used to develop functional modules such as missed medication remedy and individualized administration. The APP development scheme included requirements analysis, outline design, detailed design, software coding, software testing, software maintenance and secondary development. RESULTS The antiepileptic drug treatment management app was divided into two parts: the doctor side and the patient side. The doctor side had the functions of patient consultation, follow-up, knowledge base query, missed medication remedy plan formulation, personalized medication administration, etc. The patient side had the functions of consulting doctors, consulting pharmacists, epilepsy diary recording, popular science knowledge reading, missing medication remedy scheme query, etc. CONCLUSION The developed antiepileptic drug treatment and management APP can assist doctors and pharmacists to personalized manage patients’ antiepileptic drugs intelligently. Patients can also conveniently consult doctors and pharmacists, manage their daily medication and improve compliance through the APP.