Abstract: OBJECTIVE To comb the current status of patents related to sodium-glucose co-transporter(SGLT2) in the world, and explore the research layout and development trend, to provide reference for domestic peers. METHODS Took the global SGLT-2 patents as the research object, and conduct metrological statistics and analysis based on the Incopat patent data. RESULTS & CONCLUSION SGLT2 inhibitor patents began to increase rapidly since 2014, and entered a steady stage now. A61K, A61P, C07D patent applications were relatively active, global topics were distributed in the direction of medical configuration, specific therapeutic activity of compounds or pharmaceutical preparations, etc. The head R&D institutions mainly focused on key intermediates, hemihydrate, cotransporters, heart failure and other clustering keywords.