Abstract: OBJECTIVE To use the digital construction of inpatient pharmacy dispensing and the application and practice of intelligent dispensing, and verify the benefits of digital pharmacy construction through cost accounting, pharmacist dispensing management, performance management, workload assessment, etc. To provide solutions for intelligent drug dispensing in hospital pharmacies. METHODS The pharmacy intelligent dispensing system software was jointly innovated by pharmacists and information software engineers. Taking the real data generated from an inpatient pharmacy in a tertiary hospital(1 000 planned beds) as the research object, the workload of pharmacists’ dispensing, the statistics of shift and drug return, the statistics of drug dispensing times, and the cost accounting and benefit analysis were conducted. RESULTS The application of the intelligent pharmacy dispensing system could reduce the printing paper cost of the inpatient pharmacy dispensing process by about 28.2 thousand yuan per year. In the dispensing post, the printing time of dispensing single sheet could be saved by 3.4 h·d^-1 by calculating the number of items of taking medicine. (1 012±287)items·d^-1 could be saved, and 4.3 h·d^-1 could be saved in the time consumption of drug return. The working time of printing and returning drugs in the dispensing post could save 7.7 h. In addition, the working time of shift handover and error record could be saved, and one pharmacy could save one working time of dispensing post every day. CONCLUSION The application and practice of the intelligent pharmacy dispensing system show that it can reduce the economic cost and time cost consumption of dispensing, improve the management quality, quickly count the workload of pharmacists, and improve the work efficiency of pharmacy dispensing.