Abstract: OBJECTIVE To find the research hotspots and development trends and provide foreshadowing and reference for future research,the domestic and foreign literatures related to Scutellaria baicalensis published from 2000 to 2020 were analyzed. METHODS By searching CNKI and Web of Science,using bibliometrics and CiteSpace 5.8.R3 software to visually display the research authors,research institutions and keywords,and combined with the method of information extraction to analyze the research status and development trend of Scutellaria baicalensis.RESULTS Chinese Journal of Experimental Traditional Medical Formulae and Journal of Ethnopharmacology were the most published journals in Chinese and English respectively;Du Ming and Qinglong Guo were the most published authors in Chinese and English respectively;The analysis of issuing institutions showed that the institute of Traditional Chinese Medicine of the Chinese Academy of Traditional Chinese Medicine and China Pharmaceutical University were the research institutions that published the most Chinese and English documents;Keyword analysis of Chinese and English literature showed that the research of Scutellaria baicalensis mainly focuse on metabolomics,chemical composition,pharmacological effects,pharmacokinetics,mechanism of action and insulin resistance.CONCLUSION Mechanism research,pharmacokinetics and insulin resistance may be the research focus of Scutellaria baicalensis in the future.At present,research on Scutellaria baicalensis is still in the development stage,and it is necessary to focus on the in-depth research and strengthen the cooperation of authors or institutions.