Abstract: Children's pharmaceutical preparations have received a lot of attention. However, current children's pharmaceutical preparations still have group problems such as fewer types of preparations, low excipient safety, inappropriate specifications and poor compliance with medication. In view of the problems of children's pharmaceutical preparations, this review summarized some innovative development strategies for children's pharmaceutical preparations, especially analyzing and pointing out the advantages and application prospects of 3D printing technology in the development of innovative children's pharmaceutical preparations. This review can provide ideas for the development of new pharmaceutical preparations for children.