Abstract: OBJECTIVE To explore the mode of cultivating professionals for drug clinical research in children in the training of postgraduates with pharmacy professional graduate students. METHODS The qualities that should be possessed by the drug clinical researchers in children were analyzed, a systematic and multi-level medical education coordination system was constructed, the curriculum system was optimized based on application orientation, the dissertation with the topic of pediatric drug therapy was selected, and the process management of training was strengthened. By promoting the change of the role and concept of postgraduates, and promoting the transformation of research achievements, the drug clinical research ability of postgraduate in children had been strengthened. RESULTS The training mode of professionals for drug clinical research in children under the cooperation of medicine and education had been preliminarily established, and the trained postgraduates met the needs of society and profession. CONCLUSION The construction of training mode based on the concept of medical education cooperation is an important way to cultivate professionals for drug clinical research in children.