Abstract: Sanchen medicine is commonly used in Mongolian medicine to clear children’s lung heat, composing of Tianzhu Huang, Saffron and Bezoar equal composition. It has the functions of clearing heat and relieving cough. It is recorded in Mongolian medicine books such as “Joy of the Audience” “Four Parts of Manna” and “Gathering of Mongolian Medicine Secrets”. However, there are differences in the dosage and medicinal materials recorded in the books. The article compares and analysis the usage, tastes, functions and clinical compatibility of Sanchen medicine in in Mongolian medicine, sorts out the records of Sanchen medicine in Mongolian medicine, the frequency of use of each component of the medicine in Mongolian medicine and the medication rule are analyzed with computer software, and the research progress of the chemical composition and pharmacological activity of each component of Sanchen medicine is briefly introduced, so as to provide a basis for the application of Sanchen medicine in the field of Mongolian medicine.