Abstract: OBJECTIVE To carry on qualitative and quantitative research of arbidol hydrochloride tablets based on quantitative nuclear magnetic resonance(qNMR). METHODS Proton signal peaks at δ:7.88 ppm of arbidol hydrochloride and δ:6.33 ppm of maleic acid were employed as quantitative peaks and internal standard peaks, respectively. NMR spectrum of mixture were collected at the temperature of 298 K with 10 s relaxation delay, 4.01 s acquisition time and 32 scanning times. And integrated the quantitative peak and internal standard peak to calculate the content. The results of qNMR and HPLC were also compared. RESULTS There was a linear relationship for arbidol hydrochloride in the range of 10.53-28.09 mg·mL^-1. The recoveries were in the range of 99.76%-101.01%. The precision and stability were good, and the methodological speciality was high. The content determination results of qNMR method were generally consistent with those of HPLC method. However, qNMR had an advantage of rapid and accuracy. CONCLUSION The established method of qNMR can be used for qualitative and quantitative analysis of arbidol hydrochloride tablets, providing a new method for quality control.