Abstract: Euonymus alatus is a traditional Chinese medicine with a long history and remarkable curative effect. Its chemical constituents include flavonoids, steroids, lignans, cardiac glycosides, alkaloids, terpenes, phenylpropanoids, phenolic acids and volatile oils. Modern studies have also shown that it has a variety of biological activities such as anti-tumor, hypoglycemic, anti-hepatic fibrosis, liver protection, anti-oxidation, antibacterial, anti-inflammatory, anti-myocardial ischemia, antipyretic diuretic and so on. In this paper, the chemical constituents and pharmacological activities of Euonymus alatus were reviewed in order to provide information for the further study of the Euonymus alatus.