Abstract: OBJECTIVE To analyze the problems in the rational application of Chinese patent medicine from the perspective of the non-traditional Chinese medicine(TCM) physicians who are the main groups of physicians prescribed TCM, in order to provide references for the development and progress of the rational use of medicines. METHODS Taking the typical report of the "China Medical Tribune" as a clue, combining with the current situation of TCM work, exploring the real reasons for the irrational use of Chinese patent medicine by non-TCM physicians. RESULTS The inaccurate understanding of Chinese patent medicine, even TCM, which was the main reason for non-TCM physicians unreasonable application. CONCLUSION The prescription rights training for proprietary Chinese patent medicine is imperative. Some measures such as training conducted according to the clinical specialties division of physicians could be considered to obtain better results.