Abstract: OBJECTIVE To evaluate the effect of medication therapy management service(MTMs) for elderly patients with chronic diseases from the perspective of humanity. METHODS From January 2018 to June 2019, the elderly patients with chronic diseases who were treated in secondary medical institutions were selected as the research objects. The pharmacists provided them MTMs. Telephone follow-up was conducted 2, 4 and 6 months after MTM and the scores of European five dimensional health scale(including EQ-5D health description system and visual analogue scale score EQ-VAS), Morisky medication adherence scale(MMAS-8) and Pittsburgh sleep quality index(PSQI) before and after the medication therapy management service were counted to evaluate the effect of management. RESULTS Before medication therapy management service, the scores of EQ-5D health description system, EQ-VAS, MMS-8 and PSQI were (0.81±0.14), (76.87±11.71), (6.52±0.87) and (9.02±3.79), respectively. Six months later, the above scores were (0.83±0.13), (81.14±11.19), (6.83±0.90) and (7.96±4.00), respectively. There were significant differences in EQ-VAS, MMAS-8 and PSQI scores before and after medication therapy management service(P<0.05). CONCLUSION MTMs can improve the health status of elderly patients with chronic diseases, improve medication adherence, and improve sleep quality. It is worth further research and promotion.