Abstract: OBJECTIVE To explore the influencing factors of intelligent dispensing quality of traditional Chinese medicine formula granules in outpatient pharmacy, so as to improve the dispensing quality of pharmacists and clinical treatment effect of traditional Chinese medicine formula granules. METHODS The dispensing condition of traditional Chinese medicine formula granules in Zhujiang Hospital, Southern Medical University from May to October 2018 was used as the control group and that controlled under PDCA cycle management from November 2018 to March 2019 was used as the observation group. The factors influencing dispensing quality between the two groups were calculated by the CMH χ² test in Excel, while the mean dispensing time was calculated using a t-test. RESULTS Compared with the control group, the mean dispensing time for the observation group was dramatically shortened(P<0.01), from 4 min 13 s down to 3 min 16 s, the loading difference of granules(P<0.01), the error rate for pasting labels by pharmacists(P<0.01) as well as the rate of forgetting to place medicine boxes were reduced(P<0.01). Besides, dosing errors, machinery breakdown and dispensing errors were also reduced. CONCLUSION Dispensing quality of traditional Chinese medicine formula granule is improved, lower error rate is achieved and patients' satisfaction is increased. PDCA circle management mode can be used in the management of intelligent dispensing of traditional Chinese medicine formula granules, and can also provides reference for applying the intelligent dispensing system by other institutions.