Abstract: OBJECTIVE To establish drug use evaluation criteria for ketorolac tromethamine injection, and evaluate its clinical medication. METHODS Based on ketorolac tromethamine injection instruction, referring to related specifications and literatures, drug use evaluation criteria for ketorolac tromethamine injection was established. The utilization of ketorolac tromethamine injection in 200 inpatients of People's Hospital of Bozhou during January 2019-December 2019 was evaluated in retrospective study. RESULTS The coincidence rate of medication indication was 83.5%, the rate of accuracy dosage and accuracy administration was 45.5%, the rate of rational duration of treatment was 75.5%, the rate of rational combined drug was 55.5%. CONCLUSION The qualified rate of ketorolac tromethamine injection in the hospital where the author is located is low. The main problems are inappropriate usage and dosage, and over-treatment medication. Special attention should be paid to the ethanol contained in ketorolac tromethamine injection excipients, to avoid disulfiram-like reactions and ensure the safety of medications for patients.