Abstract: Since December 2019, an epidemic called coronavirus disease 2019 or COVID-19 quickly spread across China, and a number of pediatric cases have been reported. Facing the COVID-19 outbreak, it is more difficult to provide pharmaceutical care for children with chronic disease. How to reduce the risk of cross-infection while ensuring the safety of medication is a problem that pediatric pharmacists should pay close attention to. Therefore, specific pharmaceutical care model has been carried out in our hospital during this particular period; and the correlative experience is summarized in three aspects: construction of drug database for COVID-19; development of internet pharmaceutical services; and multi-hierarchical pharmaceutical care strategy; and finally to provide a reasonable reference for other healthcare institutions.