Abstract: As a basic treatment, nutritional support therapy is of great significance to the treatment and prognosis of patients with COVID-19. According to the five-step rule of nutritional support therapy, individualized nutritional therapy was recommended and elaborated for different types of infection patients in this paper. For the mild, normal or convalescent patients with nutritional risk, low-ladder nutritional support therapy can be used, while patients with severe or critical illness shall choose high-ladder nutritional support therapy such as tube feeding, parenteral supplementation and total parenteral supplementation. Nutritional support therapy shall be fully used in the treatment of patients with COVID-19.