Abstract: There are many medication names recorded in ancient dictionaries. The later scholars studied the relationship between names and entities in annotation. The morphological characteristics, smell of Xiongqiong, Meiwu, Jiangli and Li are similar, it is difficult to distinguish. The thesis researchs on medication names about Xiongqiong, Meiwu, Jiangli and Li in Shuo Wen Jie Zi, Er Ya, and previous annotations of these exegesis books, herbal literature are used to analyze relevant content, and to complement each other.