Abstract: OBJECTIVE To observe the clinical efficacy of Jiawei Liuwei decoction for post-operative rehabilitation treatment of acousticular pie. METHODS One hundred and thirty cases of vocal polyp patients whom were admitted in the Beijing Anzhen Hospital, Capital Medical University from January 2016 to July 2017 were as research subjects, all the patients were divided into the control group(n=65) and the research group(n=65) by random digital form. The patients of the control group were treated with supportive laryngoscope. The patients of the study group were added Jiawei Liuwei decoction treatment on the basis of surgery. The adverse drug reactions during the treatment were observed, and the clinical symptoms scores of vocal cord polyps at 3 months after surgery were compared. The therapeutic effect of vocal cord polyps was evaluated. The recurrence of vocal cord polyps was followed up within one year. RESULTS Three months after surgery, the symptoms of patients in the study group such as hoarseness, sore throat, cough phlegm, throat foreign body sensation, vocal cord congestion, dry throat and vocal cord closure of the glottis, edge swelling and other clinical symptoms scores were significantly lower than the control group(P<0.05). The total effective rate of treatment in the study group was 93.85%, and that in the control group was 81.54% (χ²=4.561, P<0.05). During the treatment period, the overall incidence of adverse drug reactions was 4.61%. The recurrence rate of vocal cord polyps in the study group(1.52%) was significantly lower than that in the control group(10.77%)(χ²=4.795, P<0.05). CONCLUSION Compared with surgery alone, postoperative adjuvant Jiawei Liuwei decoction can significantly relieve the related clinical symptoms of vocal cord polyps, improve the overall efficacy of vocal cord polyps, prevent the recurrence of vocal cord polyps, and it have less adverse drug reactions, higher safety, which is worthy of clinical promotion and use.