Abstract: OBJECTIVE To explore the use of information technology in pharmacy management and pharmaceutical services to ensure the safety of patients' medication and improve the management of pharmaceutical affairs. METHODS The progress and experience of informatization construction in drug dispensing, pharmaceutical services and team building in facial features pharmacy of Second Xiangya Hospital of Central South University were summarized. The implementation effect was analyzed and compared, and the improvement plan was proposed. RESULTS The informationization of facial features pharmacy was relatively high, especially the establishment of a temperature and humidity monitoring management system for drug maintenance, a digital intelligent pharmacy system for hospital pharmacy dispensing, and a prescription censor platform for promoting rational drug use. The combination efficiency of medical orders in all wards were >65%, and the drug dispensing time of ophthalmology orders were all < 2 min. CONCLUSION The construction of whole process informationization helps to improve work efficiency, reduce dispensing errors, and ensure safe drug use for patients.