Abstract: OBJECTIVE To explore the effect in the compliance from the new model of pharmaceutical service "Lin'an District Parkinson's Disease Patient Association". METHODS Through the develop of the new model of pharmaceutical service in the "Lin'an District Parkinson's Disease Patient Association", medication adherence was compared between the new model management patients and non-management patients with Morisky questionnaire scores and analyzed the result. RESULTS Intervention group:Compliance which was greater than or equal to moderate(Morisky questionnaire score 0 to 2 points) was raised from 42 to 56 cases, and poor compliance(3 to 4 points) was decreased from 21 to 7 cases; Control group:Compliance which was greater than or equal to moderate(Morisky questionnaire score 0 to 2 points) was from 36 to 32 cases, poor compliance (Morisky questionnaire score 3 to 4) was from 9 to 13 cases. The intervention group had a statistically significant in compliance score after intervention (P=0.012). CONCLUSION The new model of "Parkinson's Disease Patient Association" has improved the compliance of patients, and the new model of "patient association" in pharmaceutical service is worthy of being generalized in clinical practice.