Abstract: OBJECTIVE To compare quality differences between apoplexy decoctions of phlegm-dampness-stasis prepared by different models of automatic decocting machine, such as high-pressure decocting and non-pressurized double decocting, then to optimize the decocting mode and standardize the decocting process. METHODS The decoction was prepared by automatic herb decoction machine with high-pressure and non-pressure. The content of total solids and main compounds, and the bacterial count were studied. Among them, the content of main compounds was determined by HPLC, and the bacterial count was examined by microbial limit test method in appendix of Chinese pharmacopoeia. RESULTS Compared with the high pressure decocting model, the variance analysis showed that there were significant differences in relative density, total solid content and neohespridin. These indexes were all higher in non-pressure decocting condition. The bacterial count, molds and yeasts in each sample were less than 100. CONCLUSION It is more suitable for the modified banxia baizhu tianma recipe by soaking and decocting at non-pressure, so as to provide a certain data support for the decoction of phlegm-dampness-stasis type of apoplexy.