Abstract: OBJECTIVE To evaluate the effect of combination of tea pigment and hawthorn extract on reducing weight of nutritional obesity rats. METHODS Obese model was induced by high calorie forage. The rats were divided into control group, model group, tea pigment and hawthorn extract combination high dose group (equivalent to 20 times human recommendation), low dose group (equivalent to 5 times human recommendation). Recorded quantity of forage given and surplused weekly. Weighed once a week. After drug delivery for 6 weeks, weighed, anesthetized, laparotomized to take fat around testis and kidney and then weighed these fat, calculated fat/body weight ratio. RESULTS Compared with the model group, the high and low dose group of tea pigment and hawthorn extract had no significant difference in food intake, and all dose groups could reduce weight, body fat around testis and kidney, and fat/body weight ratio, significantly in the high dose group (P<0.05). CONCLUSION Combination of tea pigment and hawthorn extract has effect on reducing weight of nutritional obesity rats.