Abstract: OBJECTIVE To establish assessment system for patient medication behavior, analysis patient medication behavior mode and potential risk, to evaluate the effect of clinical pharmacists in chronic non-communicable disease management. METHODS Questionnaire was set up to evaluate patient medication behavior, which concluded basic information, knowledge, attitude and ability. Delphi method was used to check reliability. Patients with higher risk were assessed and intervented twice. RESULTS All of 535 patients were collected, 150 of which got higher risk. After assessment and intervention, the score of patient medication behavior decreased from 9.9 to 5.8, knowledge part from 2.9 to 0.8, attitude part from 1.8 to 1.4, ability part from 2.3 to 0.7. The result was significantly deference after the intervention(P<0.05). CONCLUSION By risk assessment of patient behavior, pharmacist conducte individual patient education, the effect of which is remarkable.