Abstract: OBJECTIVE To provide references for application beyond dispensatory and dispensatory modification of Huangkui capsule. METHODS By use of literature metrology, an analysis on the clinical literatures of Huangkui capsule was made. With "Huangkui jiaonang" "Huangshukui" "Huangkui capsule" and "Abelmoschus manihot" as key words, the literatures were collected from Pubmed, Ovid, Web of Science, CNKI database, VIP database and Wangfang database. By use software EndNote X7 and Excel 2007, the collected literatures were classified and the duplicate ones were eliminated for analyzing the indications and drug combinations of Huangkui capsule. RESULTS A total of 444 literatures were accepted, including 432 clinical research literatures, 11 reviews, 1 case report, and there were 3 English literatures collected. The functions and indications recorded in the dispensatory of Huangkui capsule were eliminating dampness and heat, detoxification and detumescence and Huangkui capsule was also used to treat damp-heat syndrome of chronic kidney disease (CKD). It was reported in literatures that Huangkui capsule was not only used to treat kidney diseases, such as CKD, diabetic kidney disease, immunoglobulin A nephropathy, hypertensive nephropathy, nephropathy syndrome, anaphylactic purpura nephritis, proteinuria after renal transplantation, contrast-induced nephropathy and lupus nephritis, but also used to treat non-kindey diseases, such as recurrent urinary tract infection of postmenopausal women, primary dysmenorrhea and chronic pelvic inflammation and so on. CONCLUSION This research provides references for the dispensatory modification and secondary development of Huangkui capsule.