<sup>60</sup>Co-γ射线辐照灭菌对三七粉中三七皂苷R1含量的影响

⁶⁰Co-γ射线辐照灭菌对三七粉中三七皂苷R1含量的影响

摘要: 目的考察⁶⁰Co-γ射线辐照灭菌对三七粉中有效成分三七皂苷R1含量的影响。方法选择5，8，10 kGy 3种辐照剂量对三七粉进行辐照。采用UPLC测定，比较辐照前后三七粉的需氧菌总数、霉菌和酵母菌总数及其主要有效成分之一三七皂苷R1的含量。结果三七粉经过5 kGy剂量辐照后，已能达到卫生学标准要求，且有效成分三七皂苷R1含量较辐照前无明显变化；经过8，10 kGy剂量辐照后，三七粉中所含三七皂苷R1有明显变化。结论 ⁶⁰C_O-γ射线辐照灭菌的效果理想，但要慎重选择辐照的剂量。

Abstract: OBJECTIVE To explore the effect of ⁶⁰Co-γ ray irradiation sterilization on the content of notoginsenoside R1 in Sanqi powder. METHODS Before and after the irradiation with three doses (5, 8, 10 kGy), the contents of notoginsenoside R1 and the sums of the aerobic bacteria, mold, yeast were determined by UPLC. RESULTS After 5 kGy dose of irradiation, Sanqi powder could meet the hygienic standard, without significant change on the content of notoginsenoside R1. While after the irradiation dose of 8 kGy and 10 kGy, the content of notoginsenoside R1 changed significantly. CONCLUSION The effects of sterilization is ideal by ⁶⁰Co-γ ray. But it is crucial to give more thoughts to the right dose.