Abstract: OBJECTIVE To systematically evaluate the clinical efficacy and safety of Chinese medicine prescription of Jianpi Yiqi Hewei for the treatment of diabetic gastroparesis(DGP).METHODS PubMed, MEDLINE, The CochraneLibrary, Embase, CBM, CNKI, VIP and Wanfang Data bases were searched and eligible randomized controlled trials (RCTs) were included. According to the evaluation standard of Cochrane system, the quality of literature was evaluated and meta-analysis was conducted by RevMan 5.3 software.RESULTS Twenty-eight RCTs involving 2 370 patients were identified. Meta-analysis showed that the effects of Chinese medicine group were superior to the western medicine groupRR=1.29, 95%CI(1.24, 1.35), P<0.000 01 and in improving symptoms of abdominal distentionMD=-0.31, 95%CI(-0.42, -0.21), P<0.000 01, anorexiaMD=-0.45, 95%CI(-0.72, -0.18), P=0.001 and belchingMD=-0.32, 95%CI(-0.53, -0.10), P=0.004, the Chinese medicine group was much better than the control group. The adverse reactionsRD=-0.03, 95%CI(-0.06, -0.00), P=0.03 and recurrence rateRR=0.25, 95%CI(0.14, 0.43), P<0.000 1 of Chinese medicine group were less than western medicine group.CONCLUSION The curative effect of Chinese medicine prescription on treatment of diabetic gastroparesis is superior to western medicine. However, it is still necessary to be verified by large-scale, high-quality randomized controlled trials.