柏药灌肠液辅助少腹逐瘀胶囊治疗寒湿凝滞型慢性盆腔炎的临床研究

    Clinical Study on the Cold Dampness Stagnate Type of Chronic Pelvic Inflammation Treat by Shaofuzhuyu Capsules Plus Baiyao Rectal Solution

    • 摘要: 目的 确证柏药灌肠液辅助少腹逐瘀胶囊综合治疗寒湿凝滞型慢性盆腔炎的临床疗效,为其临床应用提供科学依据。 方法 寒湿凝滞型慢性盆腔炎患者124例,随机分为对照组和试验组。对照组口服少腹逐瘀胶囊,试验组口服少腹逐瘀胶囊同时辅助柏药灌肠液治疗,2个疗程后比较2组治疗效果。 结果 试验组治疗总愈显率75.0%,总有效率为95.3%;对照组治疗愈显率48.3%,总有效率为83.3%;2组比较差异有统计学意义(P<0.05)。试验组在改善中医证候和局部体征方面优于对照组,差异有显著性(P<0.05)。试验组在降低高切全血粘度、血浆黏度和红细胞积压方面优于对照组,差异有显著性(P<0.05)。 结论 柏药灌肠液辅助少腹逐瘀胶囊综合治疗寒湿凝滞型慢性盆腔炎,可以明显提高治疗效果,且能改善患者血液流变性,值得临床推广。

       

      Abstract: OBJECTIVE Corroborate the therapeutic effects for cold dampness stagnate type of chronic pelvic inflammation under the treatment of Shaofuzhuyu capsules plus Baiyao rectal solution, and provide scientific basis for its clinical application. METHODS The 124 patients of cold dampness stagnate type of chronic pelvic inflammation were randomly assigned into two groups named control and experimental group, respectively. The control group was orally administrated with Shaofuzhuyu capsules only. The experimental group was treated by Shaofuzhuyu capsules together with Baiyao rectal solution. The therapeutic effects between groups were compared at the end of two courses of treatment. RESULTS In the experimental group, the remarkably effective rate was 75.0% and the total efficiency was 95.3%; in the control group, the remarkably effective rate was 48.3% and the total efficiency was 83.3%; the group differences were statistically significant with P<0.05. The experimental group was better than the control group in the improvement of TCM syndromes and the local signs, the differences were statistically significant with P<0.05. The experimental group in reducing the high shear whole blood viscosity, plasma viscosity and hematocrit were better than the control group, the differences were statistically significant with P<0.05. CONCLUSION The therapeutic effect for cold dampness stagnate type of chronic pelvic inflammation under the treatment of Shaofuzhuyu capsules can be significantly enhanced with Baiyao rectal solution. The drug combination can strengthen the effect, improve the blood rheology, is worth further promotion.

       

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