| 引用本文: | 姜红宇,刘郁峰,盘雪,尹霞,王宗成.响应面法优化胡柚幼果中柚皮苷与新橙皮苷的提取工艺[J].中国现代应用药学,2017,34(11):1546-1551. |
| JIANG Hongyu,LIU Yufeng,PAN Xue,YIN Xia,WANG Zongcheng.Response Surface Methodology for Optimization of Extraction Process of Naringin and Neohesperidin from Huyou fruitlet[J].Chin J Mod Appl Pharm(中国现代应用药学),2017,34(11):1546-1551. |
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| 响应面法优化胡柚幼果中柚皮苷与新橙皮苷的提取工艺 |
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姜红宇1,2,3, 刘郁峰1, 盘雪1, 尹霞1, 王宗成1,2,3
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1.湖南科技学院, 化学与生物工程学院, 湖南 永州 425199;2.湖南科技学院, 湖南省银杏工程技术研究中心, 湖南 永州 425199;3.湖南科技学院, 湘南优势植物资源综合利用湖南省重点实验室, 湖南 永州 425199
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| 摘要: |
| 目的 优选胡柚幼果中柚皮苷与新橙皮苷的提取工艺。方法 在单因素试验的基础上，对乙醇浓度、料液比、提取时间3个因素进行响应面Box-Behnken中心组合设计优化，得到最佳提取工艺。结果 最佳提取工艺条件为乙醇浓度60%、料液比1：10、提取时间1.8 h、回流提取2次，在此条件下柚皮苷与新橙皮苷的总得率为23.44%。结论 本提取工艺方法简单、合理、稳定，为工业化生产提供了一定的依据。 |
| 关键词: 响应面分析法 胡柚幼果 柚皮苷 新橙皮苷 |
| DOI：10.13748/j.cnki.issn1007-7693.2017.11.010 |
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| 基金项目:湖南省高校科技创新团队支持计划资助（2012-318）；永州市科技计划资助项目（2016-8） |
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| Response Surface Methodology for Optimization of Extraction Process of Naringin and Neohesperidin from Huyou fruitlet |
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JIANG Hongyu1,2,3, LIU Yufeng1, PAN Xue1, YIN Xia1, WANG Zongcheng1,2,3
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1.College of chemical and biological engineering, Hunan University of Science and Engineering, Yongzhou 425199, China;2.Hunan Provincial Engineering Research Center for Ginkgo Biloba, Hunan University of Science and Engineering, Yongzhou 425199, China;3.Hunan Key Laboratory of Comprehensive Utilization of Advantage Plants Resources of Southern Hunan, Hunan University of Science and Engineering, Yongzhou 425199, China
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| Abstract: |
| OBJECTIVE To optimize the extraction process of naringin and neohesperidin from huyou fruitlet. METHODS Based on the single factor experiment, Box-Benhnken three factors (ethanol concentration, solid-liquid ratio and extraction time) experiment by response surface design was carried out. RESULTS The optimum conditions was as follows:solid to liquid ratio 1:10, 60% ethanol, extraction time 1.8 h and extraction two times. Under these conditions, the total yield of naringin and neohesperidin from huyou fruitlet was 23.44%. CONCLUSION The method is simple, reasonable, feasible and provide a experiment basis for its industrial production. |
| Key words: response surface methodology Huyou fruitlet naringin neohesperidin |
