新型局部给药系统促进创伤愈合的研究进展

魏巍; 高建青; 于莲<sup>*</sup>

引用本文:	魏巍,高建青,于莲.新型局部给药系统促进创伤愈合的研究进展[J].中国现代应用药学,2014,31(11):1417-1423.
	WEI Wei,GAO Jianqing,YU Lian.Progress on Novel Topical Drug Delivery Systems Used in Wound Healing Treatment[J].Chin J Mod Appl Pharm(中国现代应用药学),2014,31(11):1417-1423.

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新型局部给药系统促进创伤愈合的研究进展
魏巍¹, 高建青², 于莲¹
1.佳木斯大学药学院，黑龙江佳木斯 154007;2.浙江大学药学院药剂所，杭州 310058

摘要:

目的皮肤组织的创伤修复是临床常见的问题，对于创伤的治疗手段多种多样。方法对近几年的相关创伤愈合文献进行整理、分析和归纳。结果阐述了皮肤组织愈合的机制及用于创伤治疗的新型局部给药系统。结论新型的局部给药系统具有能够增加局部药物浓度、减少不良反应、促进伤口愈合、使用方便、提高患者依从性等特点，新型的给药系统用于治疗局部创伤具有巨大的市场潜力。

关键词: 皮肤创伤愈合局部给药

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Progress on Novel Topical Drug Delivery Systems Used in Wound Healing Treatment

WEI Wei¹, GAO Jianqing², YU Lian¹

1.College of Pharmacy, Jiamusi University, Jiamusi 154007, China;2.Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

Abstract:

OBJECTIVE Wound healing is a common clinical problem, there are various method for treatment. METHODS Reviewed related literatures about the recent research on wound healing. RESULTS Reviewed the mechanism of wound healing and novel topical drug delivery systems potential use in wound healing. CONCLUSION Novel topical drug delivery system has many advantages, such as higher local drug concentration, reducing the side reaction, improving the wound healing, convenient for administration, and improving patient compliance. Novel drug delivery system for the treatment of wound healing has huge market potential.

Key words: skin wound healing topical drug delivery