款冬花不同提取物对豚鼠离体回肠收缩作用的研究

王金凤<SUP>1</SUP>; 杨苏蓓<SUP>2</SUP>; 毛培江<SUP>2</SUP>

引用本文:	王金凤,杨苏蓓,毛培江.款冬花不同提取物对豚鼠离体回肠收缩作用的研究[J].中国现代应用药学,2010,27(9):781-784.
	.Study the Effects of Different Extracts of Tussilago Farara L. on the Contraction of Isolated Ileum of Guinea Pig[J].Chin J Mod Appl Pharm(中国现代应用药学),2010,27(9):781-784.

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款冬花不同提取物对豚鼠离体回肠收缩作用的研究
王金凤,杨苏蓓,毛培江

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摘要:

目的研究比较款冬花各个不同提取物对豚鼠离体回肠收缩的作用。方法通过石油醚、乙酸乙酯、CO2超临界萃取等方法制备款冬花多个提取物，将离体豚鼠回肠悬吊于克-亨试液中，观察给药后豚鼠回肠的收缩作用，计算豚鼠回肠收缩幅度抑制率。结果款冬花各个不同提取物均能降低组胺引起的豚鼠离体回肠收缩幅度。结论款冬花各个提取物能明显抑制豚鼠回肠收缩运动。

关键词: 款冬花豚鼠离体回肠组胺

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Study the Effects of Different Extracts of Tussilago Farara L. on the Contraction of Isolated Ileum of Guinea Pig

WANG Jinfeng¹ YANG Subei² MAO Peijiang²

Abstract:

OBJECTIVE To investigate and compare the effect of different extracts of Tussilago farara L. on the contraction of isolated ileum of guinea pig. METHODS By the method of petroleum, acetoacetate and supercritical CO2 , the Tussilago Farara L. was extracted Isolated ileum of guinea pig was put in K-H solution. The contraction extent of isolated ileum was observed. Inhibition ratio of the contraction extent was calculated. RESULTS Different extracts of Tussilago Farara L. decreased the contraction extent of isolated ileum of guinea pig cased by histamine. CONCLUSION The extracts of Tussilago Farara L. significantly inhibited the contraction of isolated ileum of guinea pig .

Key words: Tussilago Farara L isolated guinea pig ileum histamine