Severe Anaphylaxis after Oral Aspirin: A Case Report

A 52-year-old male underwent splenectomy due to traumatic spleen rupture. However, he had to receive the drug to anti-platelet accumulation because of the increasing number of platelet (704*10^9/L 11th day after surgery). He received oral aspirin at initial dose of 25mg (25mg/Tab.) Unexpectedly, severe allergic reaction occurred abruptly and rapidly less than 1 minute. The subsequent symptoms as follows: dizzy, pericardium distressS,dyspnea, nausea, vomiting, upper abdominal pain, defecation without control, limbs spasm, pruritus et al. Electrocardiogram monitoring showed atrial tachycardia, dropping SaO₂(70-80%) and extremely hypotension (70/40mmHg). Emergent measuresSwere carried out based on usual experiences of training practices such as mask oxygen inhalation, setting multiple intravenous lines to ensure volume expansionScapacity, tracheal intubation under general anesthesia after valium muscle injection(5mg),amount of dexamethasone(10mg, iv)also be used to rescue patient’sSlife, and so on. The patient was transferred into ICU(Intensive care unit) ward because of the aftermath of aspirin allergy. An hour latter, the patient’s conditions improved gradually. The patient discharged home a week later after rescue.