Clinical Observation of Shuxuening Injection Combined with Rosuvastatin on Unstable Angina

OBJECTIVE To investigate the therapeutic effect of Shuxuening injection combined with rosuvastatin on unstable angina. METHODS The 122 patients suffering from unstable angina were randomly selected and divided into two groups: the control group(n=60) were given routine treatment such as nitroglycerin, β-receptor blockers, and rosuvastatin taken at night 20 mg per day, while the treatment group(n=62) based on the above plus Shuxuening injection 20 mL intravenous trip, once a day. The two groups were treated for 4 weeks. The indexes of angina, sublingual nitroglycerin, electrocardiogram, blood rheology, blood lipds and serum levels of C-reactive protein were observed before and after treatment. RESULTS After treatment, the total effective rates of angina pectoris symptom in control group and treatment group were 70.0% and 91.3%, respectively, there was significant difference between the two groups(P<0.01); total effective rate of ECG were 55.0% and 71.0%, respectively, there was significant difference between the two groups(P<0.01). Blood rheology, C-reactive protein and blood lipid treatment group of level were better than the control group, there were significant difference between the two groups(P<0.05 or P<0.01). CONCLUSION The treatment of Shuxuening injection combined with rosuvastatin on unstable angina pectoris has good clinical effect and less adverse reaction.