Study and Application of Chou-Talalay Method for Anti-tumor Drug Combination

Drug combination has been widely used in the therapeutic process of many serious illness, such as anti-bacterial, anti-viral and anti-tumor therapeutic, etc. However, so far the domestic and overseas scholars about evaluation standards of the curative effects have not arrived at any agreement yet, especially the synergistic effect of drug combination. Chou-Talalay method is now generally accepted as synergy quantitative analysis method for drug combination. Aiming at the anti-tumor research field, we comprehensively reviewed the method to lay a good basis for the rational use of drugs.