Synthesis of Tetraethyl Ester of 5-Aminothiophene by Phase Transfer Catalysis

OBJECTIVE Synthesis of tetraethyl ester of 5-aminothiophene by phase transfer catalysis was studied,and the best catalysis condition was also examinated.METHODS First,5-aminothiophene was synthesized from diethyl acetone-1,3-dicarboxylate by cyclization.T