NAN Peng-juan, SUN Xiao-li, WANG Ping-an, WANG Qiao-feng, JIANG Ru. Synthesis of taxol C13 side chain using two catalyzed asymmetic reactionJ. Chinese Journal of Modern Applied Pharmacy, 2006, (2): 114-116.
Citation:
NAN Peng-juan, SUN Xiao-li, WANG Ping-an, WANG Qiao-feng, JIANG Ru. Synthesis of taxol C13 side chain using two catalyzed asymmetic reactionJ. Chinese Journal of Modern Applied Pharmacy, 2006, (2): 114-116.
NAN Peng-juan, SUN Xiao-li, WANG Ping-an, WANG Qiao-feng, JIANG Ru. Synthesis of taxol C13 side chain using two catalyzed asymmetic reactionJ. Chinese Journal of Modern Applied Pharmacy, 2006, (2): 114-116.
Citation:
NAN Peng-juan, SUN Xiao-li, WANG Ping-an, WANG Qiao-feng, JIANG Ru. Synthesis of taxol C13 side chain using two catalyzed asymmetic reactionJ. Chinese Journal of Modern Applied Pharmacy, 2006, (2): 114-116.
Synthesis of taxol C13 side chain using two catalyzed asymmetic reaction
OBJECTIVE To develop a simple and economical method to achieve taxol side chain,(2R,3S)-isoproplyl-3-benzamido-2-hydroxy-3-phenylpropionate.METHODS The taxol C13 side chain with high ees could be prepared from asymmetric aminohydroxylation(AA) and dihydro
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